As the team searches the medieval village for environmental factors contributing to Sir William's rapidly deteriorating health, Thirteen and Sir William debate the acts that define honor and loyalty, especially in regard to the 'queen' of the community, one of Sir William's most frequent visitors. House and the team take on the case of Sir William, a 'knight' in a closed-off community of men and women living according to the ideals of the High Renaissance. Meanwhile, House and Wilson compete for the affection of a new neighbor, and Chase, Thirteen and Taub attempt to play a practical joke on Foreman. But with a major deal pending, Mickey is not forthcoming with the necessary personal information the team needs to treat him.Īs Mickey's condition worsens, the team resorts to old-fashioned detective work to solve the case. When drug dealer Mickey mysteriously collapses while negotiating a sale, his partner-in-crime, Eddie, accompanies him to Princeton Plainsboro for treatment. Meanwhile, Cuddy seeks advice in her search for real estate.

With the help of the team, Wilson works to diagnose the patient more optimistic results, but when things take a turn for the worse, Wilson must address his inability to separate patient from friend. Wilson accepts even though he is reluctant to believe the cancer has returned. House wagers Wilson that the patient's symptoms are attributed to new cancer cells. When an old friend and former patient of Wilson's exhibits paralysis in his right arm, Wilson puts himself on the case.

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